Cipro iv (ciprofloxacin) is a synthetic antimicrobial agent for intravenous (iv) administration. ciprofloxacin, a fluoroquinolone, is 1 cyclopropyl 6 fluoro 1,4 dihydro 4 oxo 7 (1piperazinyl) 3quinolinecarboxylic acid. its empirical formula is c 17 h 18 fn 3 o 3 and its chemical structure is:. Cipro iv is indicated for treatment of plague, including pneumonic and septicemic plague, due to yersinia pestis (y. pestis) and prophylaxis for plague in adults and pediatric patients from birth to 17 years of age. efficacy studies of ciprofloxacin could not be conducted in humans with plague for feasibility reasons. Nda 019857 cipro iv fda approved 25 february 2011 2 clinical pharmacology absorption following 60 minute intravenous infusions of 200 mg and 400 mg ciprofloxacin to normal volunteers, the mean maximum serum concentrations achieved were 2.1 and 4.6 µg ml, respectively; the concentrations at 12 hours were 0.1 and 0.2 µg ml, respectively. Ciprofloxacin 10 mg ml intravenous solution. uses, side effects, and more. warnings: quinolone antibiotics (including ciprofloxacin) may cause serious and possibly permanent tendon damage (such. Cipro oral dosage. equivalent cipro iv dosage. 250 mg tablet every 12 hours. 200 mg intravenous every 12 hours. 500 mg tablet every 12 hours. 400 mg intravenous every 12 hours. 750 mg tablet every 12 hours. 400 mg intravenous every 8 hours.